
National Antimicrobial Resistance Monitoring System (NARMS)
The National Antimicrobial Resistance Monitoring System (NARMS) is an interagency, collaborative partnership with state and local public health departments, the U.S. Food and Drug Administration (FDA), the Centers for Disease Control and Prevention (CDC), and the U.S. Department of Agriculture (USDA).
This national public health surveillance system tracks changes in antimicrobial susceptibility of select foodborne enteric bacteria found in ill people (CDC), retail meats (FDA), and food animals (USDA). The NARMS program at USDA focuses on two sampling points—samples collected from intestinal (cecal) content and carcass or food commodity samples.
NARMS Agency Partners

1996

1997

2002
NARMS Multi-Year Report 2014-2019
Read the Report- Monitor trends in antimicrobial resistance among enteric bacteria from humans, retail meats, and animals.
- Disseminate timely information on antimicrobial resistance to promote interventions which reduce resistance among foodborne bacteria.
- Conduct research to achieve better understanding of emergence, persistence, and spread of antimicrobial resistance.
- Provide data that assists FDA in decision making involving the approval of safe and effective antimicrobial drugs for animals.
2022
2021
2020
In 2002, NARMS began collecting retail meat samples. This component is led by FDA’s Center for Veterinary Medicine (CVM). Retail meat surveillance is conducted through partnerships with different states, universities, and public health departments. Participating sites purchase chicken, ground turkey, ground beef, and pork chops at retail outlets and culture them for nontyphoidal Salmonella and Campylobacter. Additionally, 11 sites also culture retail meats for E. coli and 9 sites culture for Enterococcus. Additional information is available at FDA NARMS.
In 1996, NARMS began collecting antimicrobial resistance data from ill people on select enteric bacteria transmitted commonly through food. This component started within the framework of CDC’s Emerging Infections Program and the Foodborne Diseases Active Surveillance Network (FoodNet). Human surveillance began in fourteen sites in 1996 and became nationwide in 2003. CDC performs AST on approximately 5000 human isolates per year. Additional information on CDC NARMS is available at https://www.cdc.gov/narms.
FDA, CDC, and USDA collect data from farm to fork to accomplish the NARMS objectives. NARMS data and reports are available on FSIS and partner agency websites. In addition, each year, NARMS publishes an Annual Integrated Report that summarizes the most important resistance findings from the three participating Agencies for Salmonella and Campylobacter, as well as for E. coli and Enterococcus. This report includes summary data tables, isolate level information and interactive data displays to enhance data visualization.
FSIS
- FSIS National Antimicrobial Resistance Monitoring System Cecal Sampling Program, 2014 Salmonella Report
- Quarterly Sampling Reports on Antimicrobial Resistance
- Laboratory Sampling Data
FDA
CDC
The antimicrobial drugs selected for testing are based on their importance in human and veterinary medicine and for their utility as epidemiological markers for the movement of resistant bacteria and genes between environments. NARMS partners test for bacterial susceptibility to a range of antimicrobial drugs which include 15 antimicrobial drugs for Salmonella and E. coli, 9 for Campylobacter and 16 for Enterococcus. Selected antimicrobials/antimicrobial drug classes are also ranked, by FDA, as Critically Important, Highly Important and Important using similar criteria. The specific factors and the criteria to rank the importance of antimicrobial drugs are outlined in FDA’s Guidance - GFI #152.
Whole genome sequencing (WGS) technology has become a routine part of NARMS surveillance to screen for resistance genes in enteric bacteria. Use of WGS can provide better isolate resolution including resistance genes and mobile elements and help link human and non-human resistance data.
- Long-Read Sequencing Reveals Evolution and Acquisition of Antimicrobial Resistance and Virulence Genes in Salmonella enterica
- Novel linezolid resistance plasmids in Enterococcus from food animals in the USA
- Proposed Epidemiological Cutoff Values for Ceftriaxone, Cefepime, and Colistin in Salmonella
- Comparative Analysis of Extended-Spectrum-β-Lactamase CTX-M-65-Producing Salmonella enterica Serovar Infantis Isolates from Humans, Food Animals, and Retail Chickens in the United States
- Identification of Plasmid-Mediated Quinolone Resistance in Salmonella Isolated from Swine Ceca and Retail Pork Chops in the United States
- National Antimicrobial Resistance Monitoring System: Two Decades of Advancing Public Health Through Integrated Surveillance of Antimicrobial Resistance
- WGS for Genomics and Food Safety
- Chicken parts – performance standards, serotypes and AMR
- Extraintestinal Pathogenic Escherichia coli
- Food and Drug Administration NARMS Website
- Centers for Disease Control and Prevention
- World Health Organization (WHO)Antimicrobial Resistance Website
- President’s Advisory Council on Combating Antimicrobial Resistant Bacteria (PACCARB)
- Antimicrobial Resistance Overview (AMR) (USDA)
- USDA One Health Website
In 1997, NARMS began collecting data on food animals which was led by the USDA Agriculture Research Service (ARS) through 2013. Antimicrobial susceptibility testing (AST) for non-typhoidal Salmonella began in 1997 on isolates collected from raw meat and poultry products at all slaughter facilities across the United States under the Pathogen Reduction Hazard Analysis and Critical Control Point (PR/HACCP) program. Sample types have changed over the years depending on FSIS directives: carcasses of cows/bulls, steers/heifers, market hogs1, broilers (young chickens), ground beef, ground chicken and ground turkey. Testing later expanded to include Campylobacter (1998), E. coli (2000), and Enterococcus (2003) isolated from chicken carcasses.
ARS discontinued AST of Enterococcus in PR/HACCP chicken isolates in 2012 and E. coli in 2013. Those organisms are currently tested from food animal ceca and retail meat samples. In October 2013, FSIS assumed responsibility for the AST of NARMS PR/HACCP isolates.
In March 2013, NARMS began the cecal sampling program - a collaborative effort between the FDA's Center for Veterinary Medicine (CVM) and FSIS. Samples from cecal contents are collected at slaughter facilities of selected food animals and analyzed for Salmonella, Campylobacter, Escherichia coli, and Enterococcus. The food animals that are sampled include young chickens, young turkeys, dairy cattle, beef cattle, market hogs, and sows.
In 2014, the FDA began whole genome sequencing (WGS) on Salmonella isolates collected from the cecal program. Today, FSIS performs WGS on all Salmonella and Campylobacter isolates collected from both the PR/HACCP and cecal programs
1 FSIS suspended scheduling cows/bulls from sampling in 2011 and market hogs and steer/heifers in 2012 because of the low number of positive samples.