This directive provides inspection program personnel (IPP) with the latest up-dates to the list of substances that may be used in the production of meat, poultry, and egg products. As a reminder, this directive no longer provides the complete listing of approved substances and On-Line Reprocessing (OLR) and Off-Line Reprocessing (OFLR) Antimicrobial Intervention Systems. The complete listing of approved substances and OLR and OFLR Antimicrobial Intervention Systems is available at the above link. FSIS is also providing a link to the complete list of safe and suitable ingredients, the list in 9 CFR 424.21(c) of additional acceptable food ingredients, and a Web based look-up table to search ingredients by name.

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