Awareness of non-O157 Shiga toxin-producing Escherichia coli (non-O157 STEC) as a food safety concern has increased recently. In October 2009, a Citizen’s Petition was filed with the USDA’s Food Safety and Inspection Service (FSIS) to declare all enterohemorrhagic (EHEC) Shiga toxinproducing serotypes of Escherichia coli (STEC), including non-O157 serotypes, to be adulterants within the meaning of the Federal Meat Inspection Act (FMIA). FSIS considers Escherichia coli (E. coli) O157:H7 to be an adulterant using the “ordinarily injurious” standard of the Federal Meat Inspection Act. The petition seeks to expand the current definition to include additional Shiga toxin producing E. coli, as an interpretive rule.