[Federal Register: July 25, 1996 (Rules and Regulations)]
[Page 38906-38956]
From the Federal Register Online via GPO Access [wais.access.gpo.gov]
[DOCID:fr25jy96-21]
 
[[pp. 38906-38956]] Pathogen Reduction; Hazard Analysis and Critical Control Point 
(HACCP) Systems

[[Continued from page 38905]]

[[Page 38906]]

dogs, and humans. Cysts in humans are most common in the subcutaneous 
tissues, eye and the brain.
    Foods associated with illness include: raw or undercooked pork.
    Toxoplasma gondii is a protozoan parasite that encysts in the 
tissues of a variety of mammalian hosts including pigs. Human infection 
may result in ``flu like'' symptoms in adults, late term abortions in 
pregnant women or serious congenial infections in children.
    Foods associated with illness include: raw or undercooked pork.
    Balantidium coli is a protozoal organism.
    Foods associated with illness include: raw, undercooked pork (fecal 
contamination)

Cryptosporidium spp.

    Foods associated with illness include: inadequately treated water, 
raw or undercooked veal or beef.

Chemical Hazards

    While biological hazards are of great concern because contaminated 
foods can cause widespread illness outbreaks, chemical hazards may also 
cause foodborne illnesses, although generally affecting fewer people.
    Chemical hazards can originate from four general sources:
    (1) Agriculture chemicals: pesticides, herbicides, animal drugs, 
fertilizers, etc.
    (2) Plant chemicals: cleaners, sanitizers, oils, lubricants, 
paints, pesticides, etc.
    (3) Naturally-occurring toxicants: products of plant, animal, or 
microbial metabolisms such as aflatoxins, etc.
    (4) Food chemicals: preservatives, acids, food additives, sulfiting 
agents, processing aids, etc.
    (5) Environmental contaminants: lead, cadmium, mercury, arsenic, 
PCBs.
    For many years the Food Safety and Inspection Service has conducted 
a National Residue Program to monitor the occurrence of residues from 
hazardous chemicals in meat and poultry products. Under a HACCP regime, 
frontline responsibility for control of residues from animal drugs or 
environmental contaminants will move from the government to the 
industry, although the agency will continue to verify that these 
controls and preventive measures are effective. Companies that 
slaughter livestock and poultry will probably find the FSIS National 
Residue Program Plan to be a useful document. The plan contains lists 
of compounds that might leave residues in the tissues of animals or 
birds, and provides some information on their relative risk through the 
rankings in the Compound Evaluation System. It provides information on 
which compounds FSIS has included in its annual testing program. It 
also provides information on the methods that are used to test for the 
compounds. Another FSIS document, the Domestic Residue Data Book, 
presents the results of FSIS testing. These data can help a HACCP team 
understand the overall hazard presented by various residues, although 
each company should gather information about the residue control 
performance of its own suppliers.
    Another useful reference about hazardous chemicals is the FSIS List 
of Proprietary Substances and Nonfood Compounds. This publication lists 
substances used in the preparation of product and nonfood compounds 
used in the plant environment that have been authorized by FSIS.
    Table 2 identifies some additional sources of chemical hazards. 
References listed in Section VIII can be used by the HACCP team in 
evaluating the potential chemical hazards associated with their product 
or process.

                                                           Table 2.--Types of Chemical Hazards                                                          
--------------------------------------------------------------------------------------------------------------------------------------------------------
              Location                                                                      Hazard                                                      
--------------------------------------------------------------------------------------------------------------------------------------------------------
Raw Materials.......................  Pesticides, antibiotics, hormones, toxins, fertilizers, fungicides, heavy metals, PCBs.                           
                                      Color additives, inks, indirect additives, packaging materials.                                                   
Processing..........................  Direct food additives--preservatives (nitrite), flavor enhancers, color additives.                                
                                      Indirect food additives--boiler water additives, peeling aids, defoaming agents.                                  
Building and Equipment Maintenance..  Lubricants, paints, coatings.                                                                                     
Sanitation..........................  Pesticides, cleaners, sanitizers.                                                                                 
Storage and Shipping................  All types of chemicals, cross contamination.                                                                      
--------------------------------------------------------------------------------------------------------------------------------------------------------

Physical Hazards

    Physical hazards include a variety of materials referred to as 
extraneous materials or foreign particles or objects. A physical hazard 
can be defined as any physical material not normally found in a food 
that can cause illness or injury to a person consuming the product.
    Physical hazards in finished products can arise from several 
sources, such as contaminated raw materials, poorly designed or 
maintained facilities and equipment, faulty procedures during 
processing, and improper employee training and practices. Table 3 
identifies some common physical hazards and their causes or sources.

                                                           Table 3.--Types of Physical Hazards                                                          
--------------------------------------------------------------------------------------------------------------------------------------------------------
               Hazard                                                                   Source or cause                                                 
--------------------------------------------------------------------------------------------------------------------------------------------------------
Glass...............................  Bottles, jars, light fixtures, utensils, gauge covers, thermometers.                                              
Metal...............................  Nuts, bolts, screws, steel wool, wire, meat hooks.                                                                
Stones..............................  Raw materials.                                                                                                    
Plastics............................  Packaging materials, raw materials.                                                                               
Bone................................  Raw material, improper plant processing.                                                                          
Bullet/BB Shot/Needles..............  Animals shot in field, hypodermic needles used for infections.                                                    
Jewelry.............................  Pens/pencils, buttons, careless employee practices.                                                               
--------------------------------------------------------------------------------------------------------------------------------------------------------


[[Page 38907]]



Section II

Controls and Critical Limits for Biological, Chemical, and Physical 
Hazards
    When all significant biological, chemical, and physical hazards are 
identified along with their points of occurrence, the next task is to 
identify measures to prevent the hazards from compromising the safety 
of the finished product.
    Preventive measures or controls can be defined as physical, 
chemical, or other factors that can be used to remove or limit an 
identified hazard. When considering preventive measures or controls, a 
limit must be established--this is the criterion that must be met to 
ensure safety. For example, proper heat treatment will control some 
pathogenic bacteria, and it is thus crucial to know what time/
temperature combinations constitute proper heat treatment for various 
products; these time/temperature combinations are the critical limits. 
Another example of a preventive measure for a biological hazard is the 
chlorination of poultry chiller water to prevent cross contamination of 
carcasses with Salmonella.
    With identified physical hazards, the most common preventive 
measures may be visual examinations of product or the use of a metal 
detector. Chemical hazards associated with raw materials may be 
controlled through detailed product specifications, letters of 
guarantee, or purchase specifications.
    Tables 4, 5, and 6 identify preventive measures that may be 
considered by the HACCP team. Table 7 gives some examples of regulatory 
limits.

    Table 4.--Examples of Preventive Measures for Biological Hazards    
------------------------------------------------------------------------
                Pathogen                  Preventive measure or control 
------------------------------------------------------------------------
Bacillus cereus........................  Proper holding and cooling     
                                          temperatures of foods; thermal
                                          processing of shelf-stable    
                                          canned food.                  
Campylobacter jejuni...................  Proper pasteurization or       
                                          cooking; avoiding cross-      
                                          contamination of utensils,    
                                          equipment; freezing;          
                                          atmospheric packaging.        
Clostridium botulinum..................  Thermal processing of shelf-   
                                          stable canned food; addition  
                                          of nitrite and salt to cured  
                                          processed meats; refrigeration
                                          of perishable vacuum packaged 
                                          meats; acidification below pH 
                                          4.6; reduction of moisture    
                                          below water activity of 0.93. 
Clostridium perfringens................  Proper holding and cooling     
                                          temperatures of foods; proper 
                                          cooking times and             
                                          temperatures; adequate cooking
                                          and avoidance of cross-       
                                          contamination by unsanitary   
                                          equipment or infected food    
                                          handlers.                     
Listeria monocytogenes.................  Proper heat treatments; rigid  
                                          environmental sanitation      
                                          program; separation of raw and
                                          ready-to-eat production areas 
                                          and product.                  
Salmonella spp.........................  Proper heat treatment;         
                                          separation of raw and cooked  
                                          product; proper employee      
                                          hygiene; fermentation         
                                          controls; decreased water     
                                          activity; withdrawing feed    
                                          from animals before slaughter;
                                          avoiding exterior of hide from
                                          contacting carcass during     
                                          skinning; antimicrobial       
                                          rinses; scalding procedures;  
                                          disinfecting knives.          
Staphylococcus aureus..................  Employee hygiene; proper       
                                          fermentation and pH control;  
                                          proper heat treatment and post-
                                          process product handling      
                                          practices; reduced water      
                                          activity.                     
Yersinia enterocolitica................  Proper refrigeration; heat     
                                          treatments; control of salt   
                                          and acidity; prevention of    
                                          cross-contamination.          
------------------------------------------------------------------------


     Table 5.--Examples of Preventive Measures for Chemical Hazards     
------------------------------------------------------------------------
                 Hazard                         Preventive measure      
------------------------------------------------------------------------
Naturally-Occurring Substances.........  Supplier warranty or guarantee;
                                          verification program to test  
                                          each supplier's compliance    
                                          with the warranty or          
                                          guarantee.                    
Added Hazardous Chemicals..............  Detailed specifications for    
                                          each raw material and         
                                          ingredient; warranty or letter
                                          of guarantee from the         
                                          supplier; visiting suppliers; 
                                          requirement that supplier     
                                          operates with a HACCP plan;   
                                          testing program to verify that
                                          carcasses do not have         
                                          residues.                     
In-Process Chemicals...................  Identify and list all direct   
                                          and indirect food additives   
                                          and color additives; check    
                                          that each chemical is         
                                          approved; check that each     
                                          chemical is properly used;    
                                          record the use of any         
                                          restricted ingredients.       
------------------------------------------------------------------------


     Table 6.--Examples of Preventive Measures for Physical Hazards     
------------------------------------------------------------------------
                 Hazard                         Preventive measure      
------------------------------------------------------------------------
Foreign objects in raw materials.......  Supplier's HACCP plan; use of  
                                          specifications, letters of    
                                          guarantee; vendor inspections 
                                          and certification; in-line    
                                          magnets; screens, traps, and  
                                          filters; in-house inspections 
                                          of raw materials.             
Foreign objects in packaging materials,  Supplier's HACCP plan; use of  
 cleaning compounds, etc.                 specifications, letters of    
                                          guarantee; vendor inspections 
                                          and certification; in-house   
                                          inspections of materials.     
Foreign objects introduced by            In-line metal detectors; visual
 processing operations or employee        product examinations; proper  
 practices.                               maintenance of equipment;     
                                          frequent equipment            
                                          inspections.                  
------------------------------------------------------------------------


[[Page 38908]]



              Table 7.--Some Examples of Regulatory Limits              
------------------------------------------------------------------------
                                                              Regulatory
              Hazard                   Regulatory limit        citation 
------------------------------------------------------------------------
biological: Microbial growth due   All poultry must be       Sec.  381.6
 to temperature abuse-Poultry       chilled immediately                6
 Chilling.                          after processing to a               
                                    temperature of 40                   
                                    deg.F or less.                      
chemical: Excess chemicals         Chemicals used are        Sec.  318.7
 contact product.                   approved for the                    
                                    intended use and at                 
                                    appropriate amounts.                
chemical: Chemical hazard from     Edible products must be   Sec.  317.2
 packaging materials.               packaged in container              4
                                    that will not                       
                                    adulterate product or               
                                    be injurious to health.             
                                    Packaging materials                 
                                    must be covered by a                
                                    letter of guaranty.                 
biological: Trichinae in pork....  Products containing pork  Sec.  318.1
                                    muscle tissue must be              0
                                    effectively heated,                 
                                    refrigerated, or cured              
                                    to destroy any possible             
                                    live trichinae.                     
biological: Pathogens in ready to  For destruction of        Sec.  318.1
 eat products.                      pathogens that may                 7
                                    survive a dry heat                  
                                    process. One of the                 
                                    time/temperature                    
                                    combinations for cooked             
                                    beef, roast beef, and               
                                    cooked corned beef;                 
                                    e.g., 143  deg.F\61.7               
                                    deg.C minimum                       
                                    temperature at minimum              
                                    time of 6 minutes.                  
physical: Extraneous material      Sampled carcasses         Sec.  381.7
 found on post chill examination    observed for                       6
 of poultry carcasses.              conformance with post               
                                    chill criteria,                     
                                    including unidentified              
                                    foreign material.                   
------------------------------------------------------------------------

Section III

Table 8.--Red Meat (Beef) Slaughter Hazards and Controls Use of 
Information
    This section contains examples of common process steps in beef 
slaughter. With each processing step, shown in the first column, you 
will find an ``X'' in the next three columns to tell you if there is a 
Biological hazard in column 2, a Chemical hazard in column 3, or a 
Physical hazard in column 4. Column 5 describes the hazard(s), and the 
last column lists some relevant controls or preventive measures. This 
table should be used in conjunction with the process flow diagram 
developed by your HACCP team for your plant's beef slaughter process.

                                       Table 8.--Red Meat Slaughter: Beef                                       
----------------------------------------------------------------------------------------------------------------
                                                       Description of biological,                               
 Red meat slaughter-beef: examples of                     chemical, or physical        Controls or preventive   
           processing steps             B    C    P      hazards for the process              measures          
                                                                  steps                                         
----------------------------------------------------------------------------------------------------------------
Receiving & Holding..................        X        --Residues present in edible  --Residue certification     
                                                       tissues above tolerances.     presented for live         
                                                                                     animal(s).                 
Skinning.............................   X             --Micro contamination of      --Skinning procedures are   
                                                       carcass surface due to        accomplished without hair  
                                                       contaminated outside hide     or visible fecal           
                                                       surface--contamination of     contamination of the       
                                                       carcass from floor--cross-    carcass.--Careful employee 
                                                       contamination.                practices.--Udder and      
                                                                                     puzzle removal are         
                                                                                     accomplished without       
                                                                                     contamination of edible    
                                                                                     product.                   
Evisceration.........................   X             --cross-contamination from    --Esophagus is tied to      
                                                       broken viscera.               prevent escape of stomach  
                                                                                     contents--Bung is dropped  
                                                                                     with sanitized knife and   
                                                                                     bagged to prevent escape of
                                                                                     feces--Viscera are removed 
                                                                                     intact.                    
Final Wash...........................   X             --growth of pathogens         --Final wash: Temperature:  
                                                       through insufficient wash.    90-100 deg.F Pressure: 345-
                                                                                     2070 kpa (50-300 psi)--    
                                                                                     Steam Pasteurization:      
                                                                                     Temperature: 195 deg.F or  
                                                                                     greater at surface Dwell   
                                                                                     time: 5-15 seconds in      
                                                                                     cabinet.                   
Chilling.............................   X             --growth of pathogens.......  --Surface temperature <ls-  
                                                                                     thn-eq>40 deg.F as soon as 
                                                                                     possible--Carcasses spaced 
                                                                                     a minimum of 1 inch apart. 
Receiving-Packaging Materials and Non        X        --contamination from          Letters of guarantee on file
 Beef Supplies.                                        deletious chemicals present   for all packaging materials/
                                                       in the packaging materials.   non-poultry supplies used  
                                                                                     by the establishment.      
Storage-Non Beef Supplies............             X   --contamination of stored     Examine to ensure no visible
                                                       packing materials/supplies    foreign material on/in non-
                                                       from foreign material.        poultry supplies or        
                                                                                     packaging materials.       
----------------------------------------------------------------------------------------------------------------

Section IV

Table 9.--Poultry Slaughter Hazards and Controls
Use of Information
    This section contains examples of common process steps in poultry 
slaughter. With each processing step, shown in the first column, you 
will find an ``X'' in the next three columns to tell you if there is a 
Biological hazard in column 2, a Chemical hazard in column 3, or a 
Physical hazard in column 4. Column 5 describes the hazard(s), and the 
last column lists some relevant controls or preventive measures. This 
table should be used in conjunction with the process flow diagram 
developed by your HACCP team for your plant's poultry slaughter 
process.

[[Page 38909]]



                                           Table 9.--Poultry Slaughter                                          
----------------------------------------------------------------------------------------------------------------
                                                       Description of biological,                               
    Poultry slaughter: examples of                        chemical, or physical        Controls or preventive   
           processing steps             B    C    P      hazards for the process              measures          
                                                                  steps                                         
----------------------------------------------------------------------------------------------------------------
Scalding.............................   X             --contamination from          --Fresh water input to      
                                                       scalding medium.              achieve a minimum of 1     
                                                                                     quart per bird             
                                                                                    --Temperature of the scald  
                                                                                     water maintained at        
                                                                                     appropriate levels (e.g.,  
                                                                                     <gr-thn-eq>126 deg.F)      
                                                                                    --Maintain counterflow      
                                                                                     scalding unit function     
                                                                                    --Post scald wash has       
                                                                                     sufficient pressure and    
                                                                                     volume to cover carcass    
                                                                                     with fresh (potable) water 
                                                                                     spray                      
                                                                                    --Overflow volumes are at   
                                                                                     required amounts           
Offline Procedures...................   X             --cross contamination from    Follow approved offline     
                                                       intestinal contents/exudate.  plant procedures for       
                                                                                     handling airsacculitis     
                                                                                     salvage and reprocessing   
                                                                                     for contamination (e.g., an
                                                                                     airsac salvage program that
                                                                                     transfers the carcasses to 
                                                                                     another station where the  
                                                                                     thigh, drumstick, wing tip,
                                                                                     and first wing section are 
                                                                                     salvaged and washed with   
                                                                                     chlorinated water).        
Final Wash...........................   X             --growth of pathogens.......  --A final water wash with   
                                                                                     appropriate levels of      
                                                                                     chlorinated water (e.g. 20-
                                                                                     50 ppm residual chlorine in
                                                                                     the water).                
                                                                                    --Sufficient water volume   
                                                                                     and pressure for equipment 
                                                                                     operation and sufficient   
                                                                                     dwell time in the final    
                                                                                     washer to remove visible   
                                                                                     contamination on internal  
                                                                                     and external surfaces of   
                                                                                     the carcass.               
Chilling-Carcass.....................   X             --growth of pathogens.......  Deep breast muscle          
                                                                                     temperature of carcass is  
                                                                                     <ls-thn-eq> 40 deg.F within
                                                                                     the specified time from    
                                                                                     slaughter for the class of 
                                                                                     poultry.                   
                                                                                    --Maintain an adequate      
                                                                                     chlorine level in the      
                                                                                     overflow water of in-line  
                                                                                     immersion chillers (e.g.,  
                                                                                     20-50 ppm residual chlorine
                                                                                     in the incoming water).    
                                                                                    --Maintain proper water flow
                                                                                     rates (input/overflow) for 
                                                                                     continuous chillers per    
                                                                                     USDA requirements (not less
                                                                                     than \1/2\ gallon of fresh 
                                                                                     water per frying chicken   
                                                                                     with continuous overflow). 
                                                  X   --contamination from foreign  Product entering (prechill) 
                                                       material.                     and exiting (postchill) the
                                                                                     chiller system meets the   
                                                                                     criteria for defects per   
                                                                                     USDA requirements (e.g. the
                                                                                     limits are not exceed for  
                                                                                     the number and size of     
                                                                                     extraneous materials found 
                                                                                     during the postchill       
                                                                                     examination-9 CFR Sec.     
                                                                                     381.76).                   
Chilling-Giblet/Neck.................   X             --growth of pathogens.......  --Temperature and fresh     
                                                                                     water input sufficient to  
                                                                                     meet USDA requirements for 
                                                                                     giblets and necks.         
                                                                                    --Chlorination of giblet    
                                                                                     chiller water at           
                                                                                     appropriate levels for     
                                                                                     giblets and necks [e.g.,   
                                                                                     giblets must be chilled to 
                                                                                     40 deg.F within 2 hours    
                                                                                     from removal from other    
                                                                                     viscera/fresh water intake 
                                                                                     not less than 1 gallon per 
                                                                                     40 frying chickens         
                                                                                     processed-9 CFR Sec.       
                                                                                     381.66 (c)(5)].            
                                                  X   --contamination from foreign  --Visually free of hazardous
                                                       material.                     foreign material.          
                                                                                    --Defects on poultry giblet 
                                                                                     and necks meet USDA        
                                                                                     requirements (e.g., each   
                                                                                     carcass must be observed   
                                                                                     for conformance against pre
                                                                                     and post chill criteria,   
                                                                                     including unidentified     
                                                                                     foreign materials-MPI      
                                                                                     Regulations 381.76).       

[[Page 38910]]

                                                                                                                
Cut-Up/Boning/Packaging/ Labeling....   X             --growth of pathogens.......  Temperature of product does 
                                                                                     not exceed 55 deg.F during 
                                                                                     further or second          
                                                                                     processing.                
                                                                                    --Movement of product       
                                                                                     through these areas and    
                                                                                     into the cooler is timely  
                                                                                     and efficient.             
                                                                                    --A mid-shift cleanup of the
                                                                                     area(s) is performed if the
                                                                                     room temperature is not    
                                                                                     maintained at or below 50  
                                                                                     deg.F.                     
                                                                                    --Packaging/labeling        
                                                                                     materials that come into   
                                                                                     direct contact with product
                                                                                     are intact.                
Receiving-Packaging Materials and Non        X        --contamination from          Letters of guarantee are on 
 Poultry Supplies.                                     deleterious chemicals         file for all packaging     
                                                       present in the packaging      materials/non-poultry      
                                                       materials.                    supplies used by the       
                                                                                     establishment.             
Storage-Non Poultry Supplies.........             X   --contamination of stored     Examine to ensure no visible
                                                       packing materials/supplies    foreign material on/in non-
                                                       from foreign material.        poultry supplies or        
                                                                                     packaging materials.       
----------------------------------------------------------------------------------------------------------------



Section V

Table 10.--Red Meat (Swine) Slaughter Hazards and Controls
Use of Information
    This section contains examples of common process steps in swine 
slaughter. With each processing step, shown in the first column, you 
will find an ``X'' in the next three columns to tell you if there is a 
Biological hazard in column 2, a Chemical hazard in column 3, or a 
Physical hazard in column 4. Column 5 describes the hazard(s), and the 
last column lists some relevant controls or preventive measures. This 
table should be used in conjunction with the process flow diagram 
developed by your HACCP team for your plant's swine slaughter process.

                                      Table 10.--Red Meat Slaughter: Swine                                      
----------------------------------------------------------------------------------------------------------------
                                                       Description of biological,                               
Red meat slaughter-swine: Examples of                     chemical, or physical        Controls or preventive   
           processing steps             B    C    P      hazards for the process              measures          
                                                                  steps                                         
----------------------------------------------------------------------------------------------------------------
Scalding.............................   X         X   --contamination from          Plant time/temperature      
                                                       scalding medium.              limits for scalding (e.g., 
                                                                                     although it may vary with  
                                                                                     facilities, a temperature  
                                                                                     of 138 to 140 deg.F is     
                                                                                     usually satisfactory).     
                                                                                    --Carcasses should remain in
                                                                                     scalding tanks long enough 
                                                                                     to loosen hair (excessive  
                                                                                     time or temperature results
                                                                                     in carcass cooking).       
                                             X   ...  --contamination with          --USDA-FDA approved chemical
                                                       chemicals..                   concentration not to exceed
                                                                                     manufacturer's             
                                                                                     recommendations.           
Dehairing............................   X   ...  ...  --contamination and growth    --Time/temperature          
                                                       of microorganisms due to      determined by plant-       
                                                       breaking of the skin from     specific testing results to
                                                       overexposure to the           remove visible hair to an  
                                                       dehairer.                     acceptable level without   
                                                                                     breaking skin.             
Evisceration.........................   X   ...  ...  --cross contamination from    --Remove all viscera intact.
                                                       equipment/utensils.          --Contaminated equipment    
                                                      --contamination from           will be clean and sanitized
                                                       stomach, intestines, and/or   before being used again.   
                                                       bladder contents.            --Training program for all  
                                                      --contamination from           employees, to include      
                                                       employee handling.            personal hygiene, product  
                                                                                     handling procedures, and   
                                                                                     sanitary dressing          
                                                                                     procedures.                
Trimming.............................   X   ...  ...  Stick wound has not been      Remove all visible stick-   
                                                       removed..                     wound related defects.     
Chilling.............................   X   ...  ...  --growth of pathogens.......  --Cool surface temperature  
                                                                                     to 40 deg. as soon as      
                                                                                     possible.                  
Receiving-Packaging Materials and Non  ...   X   ...  --contamination from          Letters of guarantee are on 
 Swine Supplies.                                       deleterious chemicals         file for all packaging     
                                                       present in the packaging      materials/non-poultry      
                                                       materials.                    supplies used by the       
                                                                                     establishment.             
Storage-Non Swine Supplies...........  ...        X   --contamination of stored     Examine to ensure no visible
                                                       packing materials/supplies    foreign material on/in non-
                                                       from foreign material.        poultry supplies or        
                                                                                     packaging materials.       
----------------------------------------------------------------------------------------------------------------


[[Page 38911]]



Section VI

Table 11.--Ingredient Hazards and Ingredient-Related Hazards
Use of Information
    This section contains an alphabetical list of ingredients commonly 
used in making meat and poultry products. For each entry you will find 
the name of the ingredient in the first column, and an ``X'' in the 
next three columns to tell you if there is a Biological hazard in 
column 2, Chemical hazard in column 3, or Physical hazard in column 4. 
Column 5 describes the hazard(s), and the last column lists some 
relevant controls or preventive measures. This table should be used in 
conjunction with the list of ingredients developed by your HACCP team 
for the products produced by the process under consideration.
    The HACCP team may find that a particular ingredient does not 
present the hazard identified in these tables. The presence or absence 
of a hazard can be influenced by the ingredient source and company. 
Also, Ingredient Specifications, provided by the supplier to the 
establishment, may give details on the material/ingredient being sold, 
including statements that the materials/ingredients are food grade and 
are free of harmful components. For example, the ingredient 
specifications for dried legumes might state that there will be fewer 
than 5 small rocks or stones per 10 pound bag and that no harmful 
pesticides were used in the growing process.

                                          Table 11.--Ingredient Hazards                                         
----------------------------------------------------------------------------------------------------------------
                                                       Description of biological,                               
        Examples of ingredient          B    C    P   chemical, or physical hazard     Controls or preventive   
                                                           for the ingredient                 measures          
----------------------------------------------------------------------------------------------------------------
Acidifiers...........................  ...   X   ...  --toxicological effects if    --Ingredients purchased     
                                                       limits are exceeded.          under a Letter of          
                                                                                     Guarantee.                 
                                                                                    --Ingredients purchased     
                                                                                     based on producer/provider 
                                                                                     ingredient specifications. 
Anticoagulants.......................  ...   X   ...  --toxicological effect if     --Ingredients purchased     
                                                       limits are exceeded.          under a Letter of          
                                                                                     Guarantee.                 
                                                                                    --Ingredients purchased     
                                                                                     based on producer/provider 
                                                                                     ingredient specifications. 
Antifoaming agents...................  ...   X   ...  --toxicological effect if     --Ingredients purchased     
                                                       limits are exceeded.          under a Letter of          
                                                                                     Guarantee.                 
                                                                                    --Ingredients purchased     
                                                                                     based on producer/ provider
                                                                                     ingredient specifications. 
Antioxidants.........................  ...   X   ...  --toxicological effect if     --Ingredients purchased     
                                                       limits are exceeded.          under a Letter of          
                                                                                     Guarantee.                 
                                                                                    --Ingredients purchased     
                                                                                     based on producer/provider 
                                                                                     ingredient specifications. 
Batter/Breading......................   X   ...   X   --growth of pathogens due to  --Temperature controls for  
                                                       improper storage and          use                        
                                                       handling.                    --Ingredient specification  
                                                      --foreign material             sheet identifying the      
                                                                                     required parameters the    
                                                                                     ingredient must meet.      
                                                                                    --Where applicable,         
                                                                                     ingredients must be        
                                                                                     pathogen-free.             
Beef (fresh, frozen).................   X   ...  ...  --growth of pathogens due to  --Product temperature must  
                                                       improper storage and          be 40 degrees F or less at 
                                                       handling.                     receiving.                 
                                                                                    --Product must meet         
                                                                                     establishment purchase     
                                                                                     specifications.            
                                                                                    --Product must be produced  
                                                                                     under a HACCP plan.        
Binders/Extenders....................  ...   X    X   --foreign material..........  --Ingredients purchased     
                                                                                     under a Letter of          
                                                                                     Guarantee.                 
                                                                                    --Ingredients purchased     
                                                                                     based on producer/ provider
                                                                                     ingredient specifications. 
Bleaching agents.....................  ...   X   ...  --toxicological effect if     --Ingredients purchased     
                                                       limits exceeded.              under a Letter of          
                                                                                     Guarantee.                 
                                                                                    --Ingredients purchased     
                                                                                     based on producer/ provider
                                                                                     ingredient specifications. 
Blood................................   X   ...  ...  --growth of pathogens from    --Ingredient specification  
                                                       improper handling and         sheet identifying the      
                                                       storage.                      required parameters the    
                                                                                     ingredient must meet.      
                                                                                     --Where applicable,        
                                                                                     ingredients must be        
                                                                                     pathogen-free.             
                                                                                     --Meet appropriate temp.   
Boneless beef........................   X   ...   X   --growth of pathogens due to  --Product temperature must  
                                                       improper handling and         be 40 degrees F or less at 
                                                       storage.                      receiving.                 
                                                       --foreign particle            --Product must meet        
                                                       contamination, e.g., metal    establishment purchase     
                                                       fragments or bone.            specifications.            
                                                                                     --Product must be produced 
                                                                                     under a HACCP plan.        
                                                                                     --Visual examination of    
                                                                                     product for foreign        
                                                                                     materials.                 

[[Page 38912]]

                                                                                                                
Cooked beef..........................   X   ...   X   --growth of pathogens due to  --Receiving temperature of  
                                                       improper handling and         product must be frozen or  
                                                       storage.                      refrigerated at 40 degrees 
                                                       --foreign particle            F or below.                
                                                       contamination, e.g., metal    --Product must be received 
                                                       fragments or bone particles   from an approved supplier  
                                                       in boneless beef.             who produces the product   
                                                                                     under a HACCP plan.        
                                                                                     --Visual examination of    
                                                                                     product for foreign        
                                                                                     materials upon receipt.    
Cooked poultry.......................   X   ...   X   --growth of pathogens due to  --Receiving temperature of  
                                                       improper handling and         product must be frozen or  
                                                       storage.                      refrigerated at 40 degrees 
                                                       --foreign particle            F or below.                
                                                       contamination, e.g., bone     --Product must be received 
                                                       particles in boneless         from an approved supplier  
                                                       poultry.                      who produces the product   
                                                                                     under a HACCP plan.        
                                                                                     --Product must be          
                                                                                     organoleptically acceptable
                                                                                     at receipt.                
Cooked pork..........................   X   ...   X   --growth of pathogens due to  --Receiving temperature of  
                                                       improper handling and         product must be frozen or  
                                                       storage.                      refrigerated at 40 degrees 
                                                       --foreign particle            F or below.                
                                                       contamination, e.g., bone     --Product must be received 
                                                       particles in boneless pork.   from an approved supplier  
                                                                                     who produces the product   
                                                                                     under a HACCP plan.        
                                                                                     --Product must be          
                                                                                     organoleptically acceptable
                                                                                     at receipt.                
Coloring agents (natural)............  ...   X   ...  --Toxicological effect if     --Ingredients purchased     
                                                       limits exceeded.              under a Letter of          
                                                                                     Guarantee.                 
                                                                                     --Ingredients purchased    
                                                                                     based on producer/provider 
                                                                                     ingredient specifications. 
Coloring agents (artificial).........  ...   X   ...  --Toxicological effect if     --Ingredients purchased     
                                                       limits exceeded.              under a Letter of          
                                                                                     Guarantee.                 
                                                                                    --Ingredients purchased     
                                                                                     based on producer/provider 
                                                                                     ingredient specifications. 
Curing agents........................  ...   X   ...  --Toxico logical effect if    --Ingredients purchased     
                                                       limits exceeded.              under a Letter of          
                                                                                     Guarantee.                 
                                                                                    --Ingredients purchased     
                                                                                     based on producer/provider 
                                                                                     ingredient specifications. 
Curing accelerators..................  ...   X   ...  ---toxicological effect if    --Ingredients purchased     
                                                       limits are exceeded.          under a Letter of          
                                                                                     Guarantee.                 
                                                                                    --Ingredients purchased     
                                                                                     based on producer/provider 
                                                                                     ingredient specifications. 
Dairy products.......................   X   ...   X   --growth of pathogens due to  --Temperature control.      
                                                       improper handling and        --Ingredient specification  
                                                       storage.                      sheet identifying the      
                                                       --foreign material            required parameters the    
                                                                                     ingredient must meet.      
                                                                                    --Where applicable,         
                                                                                     ingredients must be        
                                                                                     pathogen-free.             
Eggs or egg products.................   X   ...   X   --growth of pathogens due to  --Temperature control.      
                                                       improper handling and        --Ingredient specification  
                                                       storage.                      sheet identifying the      
                                                      --foreign particle             required parameters the    
                                                       contamination, e.g., shell    ingredient must meet.      
                                                       particles in broken eggs.    --Where applicable,         
                                                                                     ingredients must be        
                                                                                     pathogen-free.             
Emulsifying agents...................  ...   X   ...  --toxicological effects if    --Ingredients purchased     
                                                       limits exceeded.              under a Letter of          
                                                                                     Guarantee.                 
                                                                                    --Ingredients purchased     
                                                                                     based on producer/provider 
                                                                                     ingredient specifications. 
Flavoring agents.....................  ...   X   ...  --toxicological effects if    --Ingredients purchased     
                                                       limits exceeded.              under a Letter of          
                                                                                     Guarantee.                 
                                                                                    --Ingredients purchased     
                                                                                     based on producer/provider 
                                                                                     ingredient specifications. 
Fruits...............................  ...   X    X   --contamination from          --Ingredient specification  
                                                       agricultural chemicals.       sheet identifying the      
                                                      --foreign material             required parameters the    
                                                                                     ingredient must meet.      
Honey................................   X   ...   X   --contamination from          --Ingredient specification  
                                                       inherent microorganisms.      sheet identifying the      
                                                      --foreign particle             required parameters the    
                                                       contamination, e.g., dirt,    ingredient must meet.      
                                                       insect parts.                                            
Legumes (dry)........................  ...  ...   X   --foreign particle            --Ingredient specification  
                                                       contamination, e.g., rocks.   sheet identifying the      
                                                                                     required parameters the    
                                                                                     ingredient must meet.      

[[Page 38913]]

                                                                                                                
Mechanically deboned product.........   X   ...   X   --growth of pathogens due to  --Product temperature must  
                                                       improper handling and         be 40 degrees F or less at 
                                                       storage.                      receiving.                 
                                                      --foreign particle            --Product must meet         
                                                       contamination, e.g., bone     establishment purchase     
                                                       particles.                    specifications.            
                                                                                    --Product must be produced  
                                                                                     under a HACCP plan.        
Mold inhibitors......................  ...   X   ...  --toxicological effect if     --Ingredient specification  
                                                       improper amounts used.        sheet identifying the      
                                                                                     required parameters the    
                                                                                     ingredient must meet.      
Mushrooms............................   X    X    X   --contamination from          --Ingredient specification  
                                                       inherent microorganisms.      sheet identifying the      
                                                      --contamination from           required parameters the    
                                                       agricultural chemicals.       ingredient must meet.      
                                                      --foreign material            --Where applicable,         
                                                                                     ingredients must be        
                                                                                     pathogen-free.             
Nuts.................................   X    X    X   --contamination from          --Ingredient specification  
                                                       inherent microorganisms.      sheet identifying the      
                                                      --contamination from           required parameters the    
                                                       agricultural chemicals.       ingredient must meet.      
                                                      --foreign particle                                        
                                                       contamination, e.g., broken                              
                                                       shells.                                                  
Packaging materials..................  ...  ...   X   --toxicological effects.....  --Use only FDA approved     
                                                                                     packaging materials.       
                                                                                    -- Each lot of packaging    
                                                                                     material must be           
                                                                                     accompanied by a Letter of 
                                                                                     Guarantee in which the     
                                                                                     manufacturer attests to    
                                                                                     compliance with FDA        
                                                                                     requirements.              
Phosphates...........................  ...   X   ...  --toxicological effect if     --Ingredients purchased     
                                                       limits are exceeded.          under a Letter of          
                                                                                     Guarantee.                 
                                                                                    --Ingredients purchased     
                                                                                     based on producer/provider 
                                                                                     ingredient specifications. 
Poultry (fresh, frozen)..............   X   ...  ...  --growth of pathogens due to  --Product temperature must  
                                                       improper handling and         be 40 degrees F or less at 
                                                       storage.                      receiving.                 
                                                                                    --Product must meet         
                                                                                     establishment purchase     
                                                                                     specifications.            
                                                                                    --Product must be produced  
                                                                                     under a HACCP plan.        
Pork (fresh, frozen).................   X   ...  ...  --growth of pathogens due to  --Product temperature must  
                                                       improper handling and         be 40 degrees F or less at 
                                                       storage.                      receiving.                 
                                                                                    --Product must meet         
                                                                                     establishment purchase     
                                                                                     specifications.            
                                                                                    --Product must be produced  
                                                                                     under a HACCP plan.        
Proteolytic enzymes--Aspergillus       ...  ...  ...  --toxicological effects if    --Ingredients purchased     
 oryzae, Aspergillus, Flavusoryzae                     limits exceeded.              under a Letter of          
 group, Bromelin, Ficin, Papain.                                                     Guarantee.                 
                                                                                    --Ingredients purchased     
                                                                                     based on producer/provider 
                                                                                     ingredient specifications. 
Partially defatted products..........   X   ...   X   --growth of pathogens due to  --Product temperature must  
                                                       improper handling and         be 40 degrees F or less at 
                                                       storage.                      receiving.                 
                                                      --foreign particle            --Product must meet         
                                                       contamination, e.g., metal,   establishment purchase     
                                                       plastic.                      specifications.            
                                                                                    --Product must be produced  
                                                                                     under a HACCP plan.        
Seafood (fresh, frozen)..............   X    X   ...  --growth of pathogens due to  --Product temperature must  
                                                       improper handling and         be 40 degrees F or less at 
                                                       storage.                      receiving.                 
                                                      --environmental               --Product must meet         
                                                       contamination.                establishment purchase     
                                                                                     specifications.            
                                                                                    --Product must be produced  
                                                                                     under a HACCP plan.        
Spices/herbs--Sterilized,               X   ...  ...  --contamination from          --Ingredient specification  
 Unsterilized.                                         microorganisms inherent to    sheet identifying the      
                                                       the ingredient.               required parameters the    
                                                      --contamination from           ingredient must meet.      
                                                       agricultural chemicals.                                  
                                                      --foreign material                                        
Sweeteners--Saccharin, Citric acid,    ...  ...  ...  --toxicological effects if    --Ingredients purchased     
 Malic acid, Monoisopropyl citrate,                    limits exceeded.              under a Letter of          
 Phosphoric acid, Monoglyceride                                                      Guarantee.                 
 citrate.                                                                           --Ingredients purchased     
                                                                                     based on producer/provider 
                                                                                     ingredient specifications. 

[[Page 38914]]

                                                                                                                
Tenderizing agents...................  ...   X   ...  --toxicological effects if    --Ingredients purchased     
                                                       limits exceeded.              under a Letter of          
                                                                                     Guarantee.                 
                                                                                    --Ingredients purchased     
                                                                                     based on producer/provider 
                                                                                     ingredient specifications. 
Variety meats........................   X   ...  ...  --growth of pathogens due to  --Product temperature must  
                                                       improper handling, storage,   be 40 degrees F or less at 
                                                       or cleaning.                  receiving.                 
                                                                                    --Product must meet         
                                                                                     establishment purchase     
                                                                                     specifications.            
                                                                                    --Product must be produced  
                                                                                     under a HACCP plan.        
Vegetables...........................   X    X    X   --growth of pathogens due to  --Ingredient specification  
                                                       improper handling and         sheet identifying the      
                                                       storage.                      required parameters the    
                                                      --contamination from           ingredient must meet.      
                                                       agricultural chemicals.                                  
                                                      --foreign material                                        
----------------------------------------------------------------------------------------------------------------



Section VII

Table 12.--Processing Hazards and Controls
Use of Information
    This section contains a list of processing hazards and controls 
commonly used in making meat and poultry products. They are listed in 
alphabetical order. For each processing step, shown in the 1st column, 
you will find an ``X'' in the next three columns to tell you if there 
is a Biological hazard in column 2, Chemical hazard in column 3, or 
Physical hazard in column 4. Column 5 describes the hazard(s), and the 
last column lists some relevant controls or preventive measures. This 
table should be used in conjunction with the process flow diagram 
developed by your HACCP team for the products produced during the 
process under consideration.

                                       Table 12.--Processing Step Hazards                                       
----------------------------------------------------------------------------------------------------------------
                                                       Description of biological,                               
                                                          chemical, or physical        Controls or preventive   
           Processing steps             B    C    P      hazards for the process              measures          
                                                                  steps                                         
----------------------------------------------------------------------------------------------------------------
Acidifying (also see Pickling,          X   ...  ...  --survival of pathogens due   --Shelf-stable non-heat     
 Brining).                                             to final pH>4.6.              treated acidified product  
                                                                                     must obtain a pH of 4.6 or 
                                                                                     lower.                     
Aging (Meats)........................   X   ...  ...  --growth/survival of          --The temperature of the    
                                                       pathogens from                aging room will not exceed 
                                                       inappropriate storage         40 degrees Fahrenheit.     
                                                       temperatures and humidity    --Product temperature does  
                                                       (inadequate product water     not exceed 40 degrees      
                                                       activity (a<INF>w)).               Fahrenheit throughout the  
                                                      --growth of pathogens due to   aging process.             
                                                       rise in the pH due to        --The aging process will not
                                                       development of surface        exceed seven days.         
                                                       molds.                                                   
Boning...............................   X   ...  ...  --contamination by pathogens  --Careful employee practices
                                                       in product accumulations      to make sure that there is 
                                                       (e.g., cutting boards,        no contamination of the    
                                                       conveyor belts, utensils      product.                   
                                                       and other equipment).        --Equipment and utensils are
                                                      --cross-contamination of       washed and sanitized       
                                                       product by equipment/         immediately when           
                                                       utensils contaminated with    contaminated and each time 
                                                       pathogens when cutting        the employee leaves the    
                                                       through a non-apparent        working station.           
                                                       lesion (e.g., abscesses).    --All hot water sanitizers  
                                                                                     are maintained at 180      
                                                                                     degrees Fahrenheit.        
                                                                                    --Processing room           
                                                                                     temperature is maintained  
                                                                                     at 50 degrees Fahrenheit,  
                                                                                     or a midshift cleanup is   
                                                                                     performed within five hours
                                                                                     after operations begin.    
                                                      --contamination from bones,   --A boneless beef re-       
                                                       cartilage/extraneous          inspection procedure will  
                                                       material.                     be established using       
                                                                                     specifications outlined by 
                                                                                     FSIS.                      
Cooling..............................   X   ...  ...  --growth of pathogens due to  Cooked product will be      
                                                       improper temperatures.        cooled according to        
                                                      --germination of spore-        established procedures.    
                                                       forming pathogens due to                                 
                                                       slow chilling (e.g., C.                                  
                                                       perfringens).                                            
Cooking..............................   X   ...  ...  --survival of pathogens due   --Time/Temperature          
                                                       to improper procedures.       combinations are adequate  
                                                                                     to destroy the pathogens of
                                                                                     concern.                   

[[Page 38915]]

                                                                                                                
Drying (Meat)........................   X   ...  ...  --bacterial growth due to     --A water activity will be  
                                                       inadequate control over       specified that in          
                                                       time, temperature and         conjunction with other     
                                                       humidity.                     barriers will inhibit      
                                                                                     growth of pathogenic       
                                                                                     microorganisms (e.g., for  
                                                                                     shelf stable sausage A<INF>w of 
                                                                                     0.91 and a pH of 4.6).     
Filling..............................   X   ...  ...  --recontamination by          --Product will be protected 
                                                       pathogens in product          from contamination during  
                                                       accumulations.                the filling process, and   
                                                      --growth of pathogens due to   product temperature/ time  
                                                       temperature abuse.            will be maintained at or   
                                                                                     below the maximum          
                                                                                     determined to inhibit      
                                                                                     growth of pathogenic       
                                                                                     microorganisms.            
                                       ...   X   ...  --contamination from          --No lubricants or other    
                                                       lubricants.                   chemical contaminants will 
                                                                                     be allowed in or on the    
                                                                                     product.                   
Formulation..........................   X   ...  ...  --contamination by employee   --Careful employee practices
                                                       handling.                     used at all times to make  
                                                      --incorrect formulation        sure that there is no      
                                                      --contamination through        contamination of product.  
                                                       damaged packages.            --Ingredient packages will  
                                                                                     be clean and intact.       
                                                                                    --Ingredients will be added 
                                                                                     to product according to    
                                                                                     requirements outlined 9CR  
                                                                                     Sec.  318.7.               
                                       ...   X   ...  --excessive addition of       --Restricted ingredients    
                                                       restricted ingredients/       will be added to product   
                                                       additives could be toxic to   according to requirements  
                                                       the consumer.                 outlined in the 9CFR Sec.  
                                                                                     317.8.                     
Freezing (Meats).....................   X   ...  ...  --survival of parasites due   --Rapid cooling and         
                                                       to improper time/             freezing.                  
                                                       temperature application.                                 
                                                      --growth of pathogens due to                              
                                                       temperature abuse.                                       
Grinding.............................   X   ...  ...  --contamination by employee   --Careful employee practices
                                                       handling.                     to make sure that there is 
                                                      --recontamination by           no contamination of        
                                                       pathogens in product          product.                   
                                                       accumulations.                --Product will not be      
                                                                                     allowed to accumulate at   
                                                                                     the end of the grinder.    
                                                                                    --The temperature of the    
                                                                                     grinding room will be      
                                                                                     maintained at 50 degrees   
                                                                                     Fahrenheit.                
Grinding.............................  ...   X   ...  --contamination from          --Food grade lubricants will
                                                       lubricants.                   be used on areas of the    
                                                                                     machinery where a potential
                                                                                     for product contamination  
                                                                                     exists.                    
                                       ...  ...   X   --contamination from          --All boneless product will 
                                                       extraneous material.          be re-inspected before     
                                                                                     being loaded into the      
                                                                                     grinder.                   
Handling and Inspecting of Empty        X    X    X   --recontamination through     --Packaging materials and   
 Containers and Packaging Materials.                   damaged or soiled             empty containers will be   
                                                       containers/packaging          protected from             
                                                       material.                     contamination during their 
                                                                                     storage and handling.      
                                                                                    --No materials or containers
                                                                                     that appear to be          
                                                                                     contaminated with hazardous
                                                                                     foreign material will be   
                                                                                     used.                      
Mechanical Separating................   X   ...  ...  --growth of pathogens.......  --Product holding and       
                                                                                     cooling requirements       
                                                                                     outlined in 9CFR 318.18    
                                                                                     will be followed.          
                                                  X   --contamination from bone,    --The finished product will 
                                                       cartilage fragments.          meet the standards outlined
                                                      --contamination from           in 9CFR 319.5 for bone     
                                                       extraneous material.          particles and calcium.     
Packaging (also see Modified            X    X    X   --contamination from          --Closure and/or machine    
 Atmosphere Packaging, Vacuum                          packaging material.           specifications sufficient  
 Packaging Seaming, Sealing).                         --contamination through        to ensure adequate barrier 
                                                       damaged containers.           formation.                 
                                       ...  ...   X   ............................  --No detectable foreign     
                                                                                     material will be allowed in
                                                                                     or on the product or       
                                                                                     immediate product          
                                                                                     containers.                
Peeling..............................   X   ...  ...  --contamination by pathogens  --Careful employee practices
                                                       in product accumulations.     to make sure that there is 
                                                      --contamination from           no contamination of        
                                                       employee handling.            product.                   
                                                                                    --Product will not be       
                                                                                     allowed to accumulate in/on
                                                                                     peeling equipment.         
                                       ...  ...   X   --contamination from harmful  --Peeling equipment will be 
                                                       extraneous material.          maintained in a proper     
                                                                                     operating condition. No    
                                                                                     foreign material in the    
                                                                                     finished product.          

[[Page 38916]]

                                                                                                                
Receiving............................   X   ...  ...  --contamination through       --Product must be received  
                                                       damaged containers.           in sound containers and at 
                                                      --growth of pathogens due to   temperatures appropriate   
                                                       inappropriate storage         for the type of product.   
                                                       conditions (temperature,                                 
                                                       humidity).                                               
                                                      --growth of pathogens due to                              
                                                       temperature abuse.                                       
                                                      --contamination from                                      
                                                       receiving equipment (pumps,                              
                                                       hoses).                                                  
                                       ...   X   ...  --cross-contamination from    --Product must be received  
                                                       non-food chemicals.           in sound containers and be 
                                                                                     accompanied by a letter of 
                                                                                     guarantee from the supplier
                                                                                     if such letter is not on   
                                                                                     file.                      
                                       ...   X   ...  --contamination from          --Product must be received  
                                                       hazardous extraneous          in sound containers and be 
                                                       material (wood, nails from    accompanied by a letter of 
                                                       pallets, plastic pieces).     guarantee from the supplier
                                                                                     if such letter is not on   
                                                                                     file.                      
Retorting............................   X   ...  ...  --inadequate application of   --A thermal process specific
                                                       scheduled process.            to the product, container  
                                                                                     type and size, and         
                                                                                     retorting system must be in
                                                                                     use. The initial product   
                                                                                     temperature and any        
                                                                                     critical factors specified 
                                                                                     for the thermal process    
                                                                                     must also be controlled.   
                                                                                     Specified retort come up   
                                                                                     procedures will be         
                                                                                     followed.                  
Reworking............................   X   ...  ...  --contamination by employee   --Careful employee practices
                                                       handling.                     to make sure that there is 
                                                      --contamination by pathogens   no contamination of        
                                                       in product accumulations.     product.                   
                                                                                    --Room temperature of       
                                                                                     storage coolers will not   
                                                                                     exceed 40 degrees          
                                                                                     Fahrenheit.                
                                       ...  ...   X   --contamination foreign       --Careful employee practices
                                                       material.                     to make sure that there is 
                                                                                     no contamination of        
                                                                                     product.                   
Shipping.............................   X   ...  ...  --growth due to improper      --Product will not be       
                                                       temperatures.                 shipped unless it is 40    
                                                                                     degrees Fahrenheit or less.
                                                                                    --Product will not be loaded
                                                                                     into transport vehicles if 
                                                                                     the trailer temperature    
                                                                                     exceeds 40 degrees         
                                                                                     Fahrenheit.                
                                       ...  ...   X   --contamination from          --All product packages will 
                                                       hazardous extraneous          be intact before shipping. 
                                                       material through damaged     --All transport vehicles    
                                                       packages.                     will be cleaned after each 
                                                                                     use and before loading of  
                                                                                     product.                   
Thawing..............................   X   ...  ...  --growth of pathogens due to  --Thawing Room temperature  
                                                       improper temperatures.        will not exceed 50 degrees 
                                                                                     Fahrenheit.                
----------------------------------------------------------------------------------------------------------------



Section VIII

REFERENCES

Hazard Analysis Critical Control Point Systems

Agriculture Canada. Food Safety Enhancement Program--Implementation 
Manual. Nepean, Ontario, Canada.
HACCP: The Hazard Analysis and Critical Control Point System in the 
Meat and Poultry Industry. 1994. American Meat Institute Foundation. 
Washington, D.C.
International Commission on Microbiological Specification for Foods. 
1989. ``Microorganisms in Foods 4. Application of hazard analysis 
and critical control point (HACCP) system to ensure microbiological 
safety and quality.'' Blackwell Scientific Publications, Boston.
National Advisory Committee on Microbiological Criteria for Foods 
(NACMCF).
March 20, 1992--Hazard Analysis and Critical Control Point System.
Int. J. Food Micr. 16: 1-23.
National Advisory Committee on Microbiological Criteria for Foods
(NACMCF). June 1993--Report on Generic HACCP for Raw Beef. Food
Micr. 10: 449-488.
Pierson, M.D. and Corlett, D.A., Jr. ed. 1992. ``HACCP/Principles 
and Applications.'' Van Nostrand Reinhold.
Stevenson, K.E. ed. 1993. ``HACCP-Establishing Hazard Analysis 
Critical Control Point Programs.'' A Workshop Manual. The Food 
Processors Institute. Washington, D.C.
Tompkin, R.B. 1990. The Use of HACCP in the Production of Meat and 
Poultry Products. J. of Food Protect. 53(9): 795-803.
Tompkin, R.B. 1995. The use of HACCP for producing and distributing 
processed meat and poultry products. In Advances in Meat Research. 
Volume 10. Hazard Analysis Critical Control Point (HACCP) in Meat, 
Poultry and Seafoods. Chapman & Hall (In Press).

Foodborne Illnesses

Bean, N.H. and Griffin, P.M. 1990. Foodborne disease outbreaks in 
the United States, 1973-1987: Pathogens, vehicles, and trends. J. 
Food Protect. 53: 804-817.
Bean, N.H. and Griffin, P.M. 1990. Foodborne disease outbreaks, 5-
year summary, 1983-1987. J. Food Protect. 53: 711.
Council for Agricultural Science and Technology. ``Risks Associated 
with Foodborne Pathogens.'' February 1993.

[[Page 38917]]

Oblinger, J.L., ed. 1988. Bacteria Associated with Foodborne 
Illnesses, A Scientific Status Summary by the Institute of Food 
Technologists Expert Panel on Food Safety and Nutrition. Food 
Technol. 42(4).
Padhye, N.V.; Doyle, M.P. 1992. E. Coli O157:H7 Epidemiology, 
pathogenesis, and methods for detection in food. J. Food Prot. 
55:55-565.
Schuchat, A., Swaminathan, B. and Broome, C.V. 1991. Epidemiology of 
human listeriosis. Clin. Microbiol. Rev. 4: 169-183.
Tauxe, R.V., ``Epidemiology of Camplyobacter jejuni infections in 
the United States and other Industrialized Nations,'' In Nachamkin, 
Blaser, Tompkins, ed. Camplyobacter jejuni: Current Status and 
Future Trends, 1994, chapter 2, pages 9-19.
Tauxe, R.V., Hargett-Bean, N., Patton, C.M. and Wachsmuth, I.K. 
1988. Campylobacter isolates in the United States, 1982-1986. In, 
CDC Surveillance Summaries, June 1988. MMWR 37 (No. SS-2) : 1-13.
Todd, E. 1990. Epidemiology of Foodborne Illness: North America. The 
Lancet 336:788.

Microbiological, Chemical, and Physical Hazards

Corlett, D.A., Jr. and R.F. Steir. 1991. Risk assessment within the 
HACCP system. Food Control 2:71-72.
Environmental Protection Agency. 1992. Tolerances for Pesticides in 
Foods. Title 40, Code of Federal Regulations, Part 185. U.S. 
Government Printing Office, Washington, DC.
FDA. 1989. The Food Defect Action Levels. FDA/CFSAN. Washington, DC.
FDA. 1994. Fish and Fishery Products Hazards and Control Guide--Get 
Hooked on Seafood Safety. Office of Seafood, Washington, DC.
HACCP: The Hazard Analysis and Critical Control Point System in the 
Meat and Poultry Industry. 1994. American Meat Institute Foundation, 
Washington, DC.
International Commission on Microbiological Specification for Foods. 
1989. ``Microorganisms in Foods 4. Application of hazard analysis 
and critical control point (HACCP) system to ensure microbiological 
safety and quality.'' Blackwell Scientific Publications, Boston.
Pierson, M.D. and Corlett, D.A., Jr. ed. 1992. ``HACCP/Principles 
and Applications.'' Van Nostrand Reinhold.
Stevenson, K.E. ed. 1993. ``HACCP-Establishing Hazard Analysis 
Critical Control Point Programs.'' A Workshop Manual. The Food 
Processors Institute. Washington, DC.
USDA, 1994. Domestic Residue Data Book: 1993. USDA, FSIS, 
Washington, DC.
USDA, 1994. List of Propriety Substances and Nonfood Compounds 
Authorized for Use under USDA Inspection and Grading Programs. USDA, 
FSIS, Washington, DC.
USDA, 1995. National Residue Program Plan: 1995. USDA, FSIS, 
Washington, DC.

Internet Home Pages

Agriculture Canada/http://aceis.agr.ca
Food Law Sites/http://www.fsci.umn.edu/FoodLaw/foodlaw.html
HACCP95/http://www.cvm.uiuc.edu/announcements/haccp95/haccp95.html
Center for Disease Control/http://fftp.cdc.gov/pub/mmwr/MMWRweekly
Material Safety Data Sheets/http://listeria.nwfsc.noaa.gov/msds.html
U.S. Food and Drug Administration/http://vm.cfsan.fda.gov/list.html 
Bad Bug Book
U.S. Department of Agriculture/http://www.usda.gov

Appendix E--FSIS Sample Collection Guidelines and Procedure for 
Isolation and Identification of Salmonella from Raw Meat and Poultry 
Products

Introduction

    This sampling protocol has been prepared to support the Pathogen 
Reduction/HACCP Regulation. FSIS will be conducting a Salmonella 
testing program in support of this regulation. The regulation does not 
require establishments to conduct their own testing for Salmonella. 
However, for those who choose to conduct their own Salmonella testing 
program, the protocol outlined in this document provides detailed 
instruction for sample collection and analysis that are the same as 
those used in the FSIS Salmonella testing program for raw meat and 
poultry products.
    This protocol incorporates the use of a non-destructive sampling 
technique for sample collection of raw beef and swine carcasses. These 
techniques have been evaluated by the Agricultural Research Service and 
have been designed to give comparable results to the FSIS Nationwide 
Microbiological Baseline Data Collection Programs' excised tissue 
samples. We are continuing to improve the sponging techniques and 
welcome comments. This technique will be closely monitored during the 
first year of prevalence phase Salmonella testing. Carcass sampling for 
broiler and turkey carcasses remain the nondestructive whole bird rinse 
which was used in the Baseline Programs. Ground product sampling 
involves collecting approximately \1/2\ pound of the product.
    The analytical methods section of this protocol details the 
cultural procedures currently in use by FSIS/USDA for the examination 
of raw meat and poultry products for Salmonella. Any screening method 
under consideration for Salmonella testing must meet or exceed the 
following performance characteristics: sensitivity = <gr-thn-eq>97%, 
specificity <gr-thn-eq>96%, false-negative rate = 3%, false-positive 
rate <ls-thn-eq>4%.

Guidelines for Sample Collectors/Microbiologists

Pre-Sampling Preparation
    Prior to collecting samples, the individual designated for sample 
collection should compile a written establishment-specific sample 
collection protocol for microbiological analysis. This protocol should 
include a check list for tasks to be performed prior to sample 
collection, materials needed for sample collection, random selection 
procedures, where the samples will be analyzed (on-site versus off-
site), and other information that will aid the sample collector. 
Sampling supplies, such as sterile gloves, sterile sampling solutions, 
hand soap, sanitizing solution, etc., as well as specific materials 
needed for sampling different carcass types (i.e., specimen sponges in 
bags, if sampling cattle or swine carcasses), will need to be 
assembled.
    For cattle and hog carcass sampling, a template will be needed to 
mark off the area to sample (Figure 1). The template can be made of 
metal or aluminum foil, brown paper, etc. From a sheet larger than the 
area to be sampled, cut out a 10 cm (3.94 inches) x 10 cm square for 
sampling cattle or a 6 cm x 10 cm rectangle for swine carcass sampling. 
If a reusable metal template is used, it will need to be sanitized with 
an approved sanitizing solution (e.g. hypochlorite (bleach) solution or 
alcohol). However, the template needs to be dry before placing it on 
the carcass. Aluminum foil or paper templates can be used once and 
discarded. The foil for the template should be stored in a manner to 
prevent contamination. Since the area enclosed by the template will be 
sampled, take care not to touch this area with anything other than the 
sampling sponge. Using dirty or contaminated material may lead to 
erroneous results. If an autoclave is available, paper or aluminum foil 
templates can be wrapped in autoclavable paper and sterilized.
    The sterile sampling solution, Buffered Peptone Water (BPW), can be 
stored at room temperature. However, at least one day prior to sample 
collection, check solutions for absence of cloudiness and/or turbidity 
and place the number of containers of sampling solution (BPW) that will 
be needed for the next day's sampling in the refrigerator. DO NOT use 
solutions that are cloudy, turbid, or contain particulate matter.
    To obtain the most accurate results, samples should be analyzed as 
soon after collection as possible. However, if samples must be 
transported to an off-site laboratory, the samples need to be

[[Page 38918]]

maintained at refrigeration temperatures until transport, then shipped 
refrigerated via an overnight delivery service to the laboratory 
performing the analysis. Samples analyzed off-site must be picked up by 
the overnight courier the SAME calendar day the sample is collected. 
The sample must arrive at the laboratory no later than the day after 
the sample is collected. Samples shipped to an outside laboratory must 
be analyzed no later than the day after collection. The following 
section gives information on shipping containers and transporting 
samples to off-site facilities.

Shipping Containers and Coolant Packs

    It is important that samples fit easily into the shipping so that 
the sample bags do not break.
    Correct use of the refrigerant gel-ice packs and proper packing of 
the shipping container are necessary so that samples arrive at the 
laboratory at an acceptable temperature. Frozen samples or samples 
which are too warm are not considered valid and must not be analyzed. 
Some bacteria may be damaged by temperatures that are too cold. 
Temperatures that are too warm can allow bacteria to reproduce. 
Maintaining samples at improper temperatures may cause inaccurate 
sample results.
    The sample should be kept refrigerated, NOT FROZEN, in the shipping 
container prior to pickup by the courier. The shipping container, 
itself, should not be used as a refrigerator. However, multiple samples 
(if needed) for that day may be stored in the open shipping container 
in the cooler or refrigerator.
Random Selection of Carcasses or Ground Product for Sampling
    Samples are to be taken randomly. There are different methods of 
selecting the specific carcass for sampling that could be used but all 
require the use of random numbers. Methods could include: using random 
number tables, drawing cards, using calculator- or computer-generated 
random numbers, etc. When selecting the random numbers, use the 
method(s) currently in use at the establishment for other sampling 
programs, if other programs are currently underway.
    The carcass or ground product for sampling must be selected at 
random from all eligible carcasses. If multiple lines exist, randomly 
select the line for sample collection for that interval. Repeat the 
random selection process for the next sampling interval. Each line 
should have an equal chance of being selected at each sampling 
interval.

Cattle Carcass Selection

    The half-carcasses eligible for sampling should be selected from 
those in the cooler 12 or more hours after slaughter. Both the 
``leading'' and ``trailing'' sides of a carcass should have an equal 
chance of being selected. NOTE: If more than one shift is operating at 
the plant, the sample can be taken on any shift, provided the following 
requirements are met:
    Selection of TIME: Determine the times that carcasses chilled for 
12 or more hours will be on hand. Then randomly select a time for 
collecting samples. If samples are shipped off-site, then take into 
account that the delivery service may have limitations on pickup times.
    Selection of COOLER SITE: Select a safe and accessible site in the 
cooler for random selection of the half-carcass. This site may be 
located at the transfer chain, grading chain, or a rail that contains 
carcasses that have been chilled 12 hours or more.
    Selection of HALF-CARCASS: At the random time selected, identify a 
half-carcass (selected by your random number method) from the 
predetermined point along the chain (selected cooler site) and then 
count back five (5) half-carcasses and select the next half-carcass 
(carcass) for sampling. The reason for counting back five half-
carcasses is to avoid any possible bias during selection.

Swine Carcass Selection

    The carcasses eligible for sampling should be selected from those 
in the cooler 12 or more hours after slaughter. Every carcass should 
have an equal chance of being selected.

    Note: If more than one shift is operating at the plant, the 
sample can be taken on any shift, provided the following 
requirements are met:

    Selection of TIME: Determine the times that carcasses chilled for 
12 or more hours will be on hand. Then randomly select a time for 
collecting samples. If samples are shipped off-site, then take into 
account that the delivery service may have limitations on pickup times.
    Selection of COOLER SITE: Select a safe and accessible site in the 
cooler for random selection of the carcass. This site may be located at 
the transfer chain, or a rail that contains carcasses that have been 
chilled 12 hours or more. If there are multiple sites of the same kind, 
select one at random.
    Selection of CARCASS: At the random time selected, identify a 
carcass (selected by your random number method) from the predetermined 
point along the chain and then count back five (5) carcasses and select 
the next carcass for sampling. The reason for counting back five 
carcasses is to avoid any possible bias during selection.

Poultry Carcass Selection

    The poultry carcasses will be selected at random after chilling, at 
the end of the drip line or last readily accessible point prior to 
packing/cut-up. A WHOLE carcass is required, that is, one that has not 
been trimmed.

    Note: If more than one shift is operating at the plant, the 
sample can be taken on any shift, provided the following 
requirements are met:

    Selection of TIME: Determine the times that chilled carcasses will 
be on hand, then randomly select a time for collecting samples. If 
samples are shipped off-site, then take into account that the delivery 
service may have limitations on pickup times.
    Selection of CHILLER: If more than one chiller system is in 
operation at the time of sample collection, the chill tank from which 
the sample is selected must be randomly selected.
    Selection of POULTRY CARCASS: At the random time, identify a 
carcass (selected by your random number method) from the predetermined 
point, and then count back five (5) carcasses and select the next 
carcass for sampling. Exception: If the fifth carcass is not a WHOLE 
(untrimmed) bird, count back an additional five carcasses for sample 
selection. Remember: Each carcass must have an equal chance of being 
selected. The reason for counting back five carcasses is to avoid any 
possible bias during selection.

Raw Ground Product Selection (Beef, Pork, Chicken, Turkey)

    Raw ground product samples will be randomly selected and collected 
after the grinding process and, if possible before any addition of 
spices or seasonings, but prior to final packaging.

    Note: If more than one shift is operating at the plant, the 
sample can be taken on any shift, provided the following 
requirements are met:

    Selection of TIME: Determine the times that raw ground product will 
be produced, then randomly select a time for collecting samples. Take 
into account that the overnight delivery service may have limitations 
on pickup times, for determining sample collection time.
    Selection of GRINDER: If more than one grinder is in operation at 
the time of sample collection, the grinder from which the sample is 
selected must be randomly selected.

[[Page 38919]]

Aseptic Techniques/Sampling
    Extraneous organisms from the environment, hands, clothing, sample 
containers, sampling devices, etc., may lead to erroneous analytical 
results. Stringent requirements for microbiological analysis are 
necessary, therefore, use of aseptic sampling techniques and clean 
sanitized equipment and supplies are of utmost importance. The 
following information gives general techniques for aseptic techniques 
that are routinely used during sample collection for microbiological 
analysis.
    There should be an area designated for preparing samples, etc. A 
stainless steel, wheeled cart or table would be useful during sampling. 
A small tote or caddy could be could be easily transported to the 
location of sampling and used for carrying supplies, supporting sample 
bags when adding sterile solutions to sample bags, etc.
    Sterile gloves should be used for collecting samples. The only 
items which may contact the external surface of the glove are the 
exposed sample being collected and/or the sterile sample utensil 
(specimen sponge). Keep in mind that the outside surfaces of the sample 
container are not sterile. Do not handle the inside surface of the 
sterile sample containers. Do not touch anything else. The following 
procedure for putting on sterile gloves can be followed when collecting 
samples:
    (a) Peel open the package of sterile gloves from the top without 
contaminating (touching, breathing on, contacting, etc.) the exterior 
of the gloves.
    (b) Remove a glove by grasping it from the wrist-side opening inner 
surface which is folded. Avoid any contact with the outer surface of 
the glove. Insert the washed and sanitized hand into the glove, taking 
care not to puncture the glove or touch the outside surface of the 
glove.
    (c) Next, follow the same procedure for the hand you will use to 
physically handle the sample, using care not to contaminate the outer 
surface of the glove.
    (d) If at any time you are concerned that a glove may be 
contaminated, discard it and begin again with Step (a) above.
Preparation for Sample Collection
    Prior to collecting samples, review steps for sample collection, 
random selection procedure, etc.
    At least one or more days prior to sample collection, check 
sampling solution (BPW) for cloudiness/turbidity and refrigerate if not 
cloudy or turbid. If shipping samples to off-site facility, place 
coolant packs in freezer then pre-chill open shipping in cooler/
refrigerator.
    On the day of sampling, gather all sample collection bags, sterile 
gloves, sanitizer, hand soap, sterile solutions for sampling, and 
specific materials listed under the Materials section of the sample 
collection section for the type of carcass to be sampled.
    Label the sample bags before starting sampling procedure. Use 
permanent ink. If you are using paper labels, it is important that the 
label be applied to the bag at normal room temperature; it will not 
stick if applied in the cooler.
    Outer clothing (frocks, gloves, head gear, etc.) worn in other 
areas of the plant should be removed before entering the sampling area 
or preparing to collect samples. Replace outer clothing removed earlier 
with clean garments (i.e. laboratory coat) that have not been directly