U.S. Department of Agriculture
Food Safety and Inspection Service
Washington, DC 20250
SECTION 4: MONITORING PLAN COMPOUND SELECTION CRITERIA AND TABLE KEYS
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Criterion 1. Contribution to the meat and poultry supply - The slaughter classes have been divided into four different groups, based on their relative production level in pounds. Each group has been assigned a point value, as follows:
Criterion 2. Non-uniform consumption patterns - This category refers to either
of two situations: (1) Where consumption of a small slaughter class (labeled as "very low"
or "low" slaughter volume in Criterion 1) is concentrated within a specific segment
of the population (in this case, high residue levels in this slaughter class could lead to
disproportionate exposure of this subpopulation); or: (2) Where consumption of any slaughter
class is particularly high among infants and children, since these subpopulations may be more sensitive
to chemical residues.
Criterion 3. International considerations - This category reflects any unusual
concern of the international community for this compound/slaughter class pair.
Criterion 4. Residue violations from the monitoring program - This column represents the overall percent of samples found violative over the five year period 1991 - 1995. The levels of violations have been divided into four groups and assigned the following point values:
Criterion 5. Non-violative residue findings from the monitoring program - This column represents the overall percent of samples found to have positive, but non-violative, residue levels over the five year period 1991 -1995. The levels of non-violative positives have been divided into four groups and assigned the following point values:
Criterion 6. Violative findings from the Residue Violation Information System (RVIS) - This column represents the total number of violative samples listed in RVIS over the three year period 1993 - 1995. Point values were assigned by analyzing the distribution of RVIS violations within each compound class, and dividing these numbers of violation into four groups based on breakpoints within the distribution. Point values were assigned as follows:
Criterion 7. Regulatory intelligence information - This category reflects professional judgement by FSIS and FDA-CVM staff regarding the degree of misuse of the compound or compound class, based on regulatory intelligence information available from FSIS, FDA, and other Federal and State sources. This is considered as a supplement to information on violations provided by the monitoring program and RVIS and, in these cases, is scored as follows:
However, there are also cases where no historical information is available for residue violations in a particular compound/slaughter class pair. In these cases, values of "0" were, by default, assigned to columns 4, 5 (monitoring), and 6 (RVIS). However, "0" means that we sampled and did not find anything. It should not be used for cases where sampling was not done. To avoid a bias against compound/slaughter class pairs that had never been sampled, points were assigned to the regulatory intelligence category as follows:
Thus, if no regulatory intelligence information were available on a compound/slaughter class pair that has been subjected to sampling, a value of 0 is assigned to this category. But if no regulatory information is available on a compound/slaughter class pair, and it has never been sampled, a value of 5 is assigned to indicate the potential for a problem to exist. Criterion 8. Industry HACCP or QA/QC plans directed toward controlling the level of the compound or compound class - This category reflects the degree of analytical testing, and other practices, used by growers and slaughter establishments to ensure that residues are kept below violative levels.
Criterion 9. Toxicological evaluation - In this category, each compound or compound class is assigned a score for toxicity, based on current EPA and FDA tolerances. The score assigned to a compound class is based on the compound(s) in that class having the lowest tolerances. For example, antibiotics were assigned a high toxicity, based on the low (<50 ppb) tolerances of penicillin and neomycin. Scoring was assigned as follows:
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URL: http://www.usda.gov/fsis/ophs/bluebook/sect4.htm
Last Updated On 03/09/1998.